GMB-475, CAS [[2490599-18-1]]

Product Overview

• Article Name: GMB-475, CAS [[2490599-18-1]]
• Biozol Catalog Number: TGM-T8488
• Supplier Catalog Number: T8488
• Alternative Catalog Number: TGM-T8488-1MLX10MM(INDMSO),TGM-T8488-1MG,TGM-T8488-2MG,TGM-T8488-5MG,TGM-T8488-10MG,TGM-T8488-25MG,TGM-T8488-50MG,TGM-T8488-100MG,TGM-T8488-200MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

GMB-475 is a BCR-ABL1 tyrosine kinase degrader based on PROTAC, overcoming BCR-ABL1-dependent drug resistance. GMB-475 targets BCR-ABL1 protein and recruits the E3 ligase Von Hippel Lindau (VHL).resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein

Product Properties

• Molecular Weight: 861.93
• Purity: 98.78%
• CAS Number: [2490599-18-1]
• Formula: C43H46F3N7O7S
• Target: STAT|||JAK|||E3 Ligase Ligand-Linker Conjugates|||Apoptosis|||PROTACs|||Bcr-Abl

Images

T8488