Trans-J-113863 serves as a potent antagonist of chemokine receptors CCR1 and CCR3, effectively inhibiting MIP-1alpha-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants, with respective half-maximal inhibitory concentrations (IC50) of 9.57 nM and 93.8 nM [1] [2].
Molecular Weight:
655.44
CAS Number:
[202796-42-7]
Formula:
C30H37Cl2IN2O2
Target:
Others|||CCR
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