TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 µM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nomega-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].
Molecular Weight:
450.8
CAS Number:
[2319722-53-5]
Formula:
C21H16ClN2NaO6
Target:
Others|||Apoptosis|||PAI-1
T84891
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