alpha-Cortolone, a metabolite of the glucocorticoid cortisol (hydrocortisone), is produced through the action of 20alpha-hydroxysteroid dehydrogenase (20alpha-HSD) via a tetrahydrocortisone (THE) intermediate. Studies indicate that urinary levels of alpha-cortolone are reduced in patients experiencing severe anorexia nervosa and postmenopausal women diagnosed with endometrial adenocarcinoma, in comparison to postmenopausal women without the condition.
Molecular Weight:
366.49
CAS Number:
[516-42-7]
Formula:
C21H34O5
Target:
Others
T84945
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