Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement pathway in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
Molecular Weight:
580.41
Purity:
99.88%
CAS Number:
[1903768-17-1]
Formula:
C26H23BrFN7O3
Target:
Complement System
T8509
* VAT and and shipping costs not included. Errors and price changes excepted