Monohydroxy melphalan, a degradation product and DNA alkylating agent derived from melphalan, results from melphalan hydrolysis in aqueous solutions such as cell culture medium and human plasma. It enhances DNA adducts in ML-1 myeloblastic leukemia cells based on concentration and induces cytotoxicity with an IC50 value of 28.1 µg/ml.
Molecular Weight:
359.68
CAS Number:
[2707535-88-2]
Formula:
C13H19ClN2O3?2HCl
Target:
Others|||Drug Metabolite
T85127
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