ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 µM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
Molecular Weight:
280.22
Purity:
98.65%
CAS Number:
[1610516-67-0]
Formula:
C14H8F4N2
Target:
Antibiotic
T8533
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