(Rac)-SAG, an isoform of SAG, is a potent Smoothened (Smo) receptor agonist (EC50 = 3 nM, Kd = 59 nM) that activates the Hedgehog signaling pathway and counteracts Cyclopamines inhibition of Smo [1] [2] [3].
Molecular Weight:
490.06
CAS Number:
[364590-63-6]
Formula:
C28H28ClN3OS
Target:
Smo
T85362
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