The compound 5-HT2CR agonist 1 (compound 8), a 7-chloro analogue, is a selective partial agonist for the 5-HT2C receptor, exhibiting an Emax of 71.09% and an EC50 of 121.5 nM, with no activity observed toward 5-HT2A or 5-HT2B receptors. It does not recruit beta-arrestin and shows low hERG inhibition at 10 µM [1].
Molecular Weight:
235.71
CAS Number:
[1216074-15-5]
Formula:
C13H14ClNO
Target:
5-HT Receptor
T85487
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