Antitumor Agent-100 (compound A6) is a molecular gel and apoptosis inducer targeting PDE3A-SLFN12 with an IC50 of 0.3 µM, demonstrating potent antitumor activity. This orally available agent binds to the PDE3A enzyme pocket, recruiting and stabilizing SLFN12 which disrupts protein translation and induces apoptosis [1].
Molecular Weight:
311.77
CAS Number:
[2841750-32-9]
Formula:
C17H14ClN3O
Target:
PDE|||Apoptosis
T85701
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