AR/AR-V7-IN-1 (Compound 20i) serves as an inhibitor of AR/ARV7, demonstrating an IC 50 of 172.85 nM. It effectively inhibits cell growth in the LNCaP and 22RV1 cell lines, with IC 50 values of 4.87 µM and 2.07 µM, respectively. Additionally, it shows potent tumor growth inhibition in a 22RV1 xenograft study. AR/AR-V7-IN-1 is useful in studies related to prostate cancer [1].
Molecular Weight:
660.22
CAS Number:
[2964558-54-9]
Formula:
C36H43ClFN7O2
Target:
Androgen Receptor
T85720
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