BAY-155 is a powerful and selective menin-MLL inhibitor, exhibiting an IC 50 of 8 nM. It significantly down-regulates MEIS1 gene expression while up-regulating CD11b and MNDA genes. BAY-155 also demonstrates anti-proliferative effects in AML/ALL (acute myeloid/lymphoblastic leukemia) models [1].
Molecular Weight:
567.63
CAS Number:
[2163769-52-4]
Formula:
C28H28F3N7OS
Target:
Epigenetic Reader Domain
T85802
* VAT and and shipping costs not included. Errors and price changes excepted