BKN-1, a bifunctional ligand, facilitates the tracking of mtG4s (G-quadruplexes, four-stranded DNA structures containing Hoogsteen bonds) formation via far-red emission and can induce mitochondrial dysfunction. This compound exhibits anti-tumor properties, potentially causing mtDNA loss, damaging mitochondrial integrity, reducing ATP levels, and triggering ROS imbalance, which can lead to apoptosis and autophagy [1].
Molecular Weight:
556.48
CAS Number:
[1607831-82-2]
Formula:
C31H29IN2
Target:
Apoptosis|||Autophagy
T85862
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