BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].
Molecular Weight:
436.3
CAS Number:
[1345406-09-8]
Formula:
C22H18BrN3O2
Target:
SARS-CoV
T85904
* VAT and and shipping costs not included. Errors and price changes excepted
