CYP4A11/CYP4F2-IN-2 (compound 15) serves as an orally administered inhibitor targeting CYP4A11/4F2, exhibiting IC50 values of 120 nM and 220 nM, respectively. This compound effectively suppresses 20-HETE production within the rat kidney and shows promise in mitigating the progression of diabetic nephropathy and autosomal dominant polycystic kidney disease [1].
Molecular Weight:
361.44
CAS Number:
[2280834-99-1]
Formula:
C19H27N3O4
Target:
Cytochromes P450
T86151
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