Divarasib (GDC-6036) adipate is a selective and highly potent KRAS G12C inhibitor with an impressively low IC 50 value of <0.01 µM, designed for oral administration. It covalently attaches to the switch II (SW-II) pocket in KRAS G12C, irreversibly maintaining the protein in its inactive GDP-bound state [1] [2].
Molecular Weight:
768.2
CAS Number:
[2762240-36-6]
Formula:
C35H42ClF4N7O6
Target:
Ras|||Kras
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