EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) represents the membrane-permeable version of the metal chelator EDTA. By incubating live cells with EDTA-AM, they passively absorb this compound. After entering the cell, cytoplasmic esterases break down the AM esters, liberating the active chelating agent EDTA that sequesters metal ions internally. The presence of EDTA-AM in cells leads to the cessation of mitotic progression and the decondensation of chromosomes [1] [2].
Molecular Weight:
580.49
CAS Number:
[162303-59-5]
Formula:
C22H32N2O16
Target:
Others
T86339
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