EGFR T790M/L858R-IN-7 (Compound 72), a novel pyrimidine compound, exhibits high efficacy in inhibiting the EGFR T790M and L858R mutations, with a 93% inhibition rate at 0.05 µM. It achieves its inhibitory action by specifically binding to the kinase domain of EGFR, which prevents phosphorylation activity [1].
Molecular Weight:
515.56
CAS Number:
[3032760-90-7]
Formula:
C27H29N7O4
Target:
EGFR
T86348
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