EGFR/AURKB-IN-1, CAS [[3008543-34-5]]

Product Overview

• Article Name: EGFR/AURKB-IN-1, CAS [[3008543-34-5]]
• Biozol Catalog Number: TGM-T86350
• Supplier Catalog Number: T86350
• Alternative Catalog Number: TGM-T86350-25MG,TGM-T86350-50MG,TGM-T86350-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

EGFR/AURKB-IN-1 (compound 7) serves as a dual inhibitor targeting EGFR/AURKB, effectively inhibiting the phosphorylations of L858R EGFR and AURKB with IC50 values of 0.07 and 1.1, respectively. The compound engages with the hydrophobic region I or the alphaC-helix out pocket of EGFR and the back pocket of AURKB. This binding action suppresses tumor cell growth, division, and metastasis, making it a valuable agent for cancer research [1].

Product Properties

• Molecular Weight: 396.44
• CAS Number: [3008543-34-5]
• Formula: C23H20N6O
• Target: EGFR|||Aurora Kinase

Images

T86350