EGFR-IN-97 (compound 6q), an EGFR inhibitor, demonstrates effectiveness in inhibiting Ba/F3-EGFR L858R/T790M/C797S and Ba/F3-EGFR Del19/T790M/C797S cells, exhibiting IC 50 values of 0.42 µM and 0.41 µM, respectively. Additionally, at a concentration of 0.8 µM, EGFR-IN-97 is capable of inducing apoptosis in NCI-H1975-EGFR L858R/T790M/C797S cells [1].
Molecular Weight:
624.73
CAS Number:
[3020681-05-1]
Formula:
C37H36N8O2
Target:
EGFR|||Apoptosis
T86361
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