HMC-B17 is a selective and orally bioavailable HPK1 inhibitor (IC50 = 1.39 nM) that enhances anti-PD-L1 efficacy. It significantly increases IL-2 secretion in Jurkat cells (EC50 = 11.56 nM) and can be utilized for cancer research [1].
Molecular Weight:
427.54
CAS Number:
[2935913-83-8]
Formula:
C27H29N3O2
Target:
MAPK
T86587
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