HSD17B13-IN-61 (Compound 132) acts as an inhibitor against hydroxysteroid 17beta-dehydrogenase 13 (HSD17B13), featuring an IC50 value of 0.1 µM for estradiol. This compound is utilized in the study of various health conditions, including liver diseases, metabolic diseases, and cardiovascular diseases like NAFLD or NASH. It is also relevant in the investigation of drug-induced liver injury (DILI) [1].
Molecular Weight:
542.27
CAS Number:
[2770247-26-0]
Formula:
C23H13Cl2F4N3O4
Target:
Dehydrogenase
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