JAB-2485 is a highly potent and selective inhibitor of Aurora kinase A (AURKA), boasting an IC 50 of 0.33 nM, and demonstrates approximately 1700-fold selectivity for AURKA over AURKB. It induces cell cycle arrest and apoptosis, making it a valuable compound for cancer research [1].
Molecular Weight:
503.97
CAS Number:
[2899209-55-1]
Formula:
C25H28ClF2N5O2
Target:
Aurora Kinase|||Apoptosis
T86753
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