LMP517 (NSC 781517), an indenoisoquinoline, is a potent dual TOP1 and TOP2 inhibitor that shows better antitumor activity than its parent compound LMP744 against H82 (Small Cell Lung Cancer) xenografts, inducing TOP1 cleavage complexes (TOP1ccs) and TOP2ccs [1].
Molecular Weight:
410.4
CAS Number:
[1883730-99-1]
Formula:
C22H19FN2O5
Target:
Topoisomerase
T86817
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