MG-1102 is a first-in-class dual binder of monomeric tau and pre-miRNA-146a, exhibiting specific inhibition of miRNA146a with IC 50 values of 0.21 mM for double-labeled pre-miRNA146a and 0.36 mM for mono-labeled pre-miRNA146a. It interacts with tau monomers with a K d of 3.21 mM as determined by surface plasmon resonance (SPR), positioning it as a potential multi-target-directed ligand (MTDL) for Alzheimers disease (AD) [1].
Molecular Weight:
386.47
CAS Number:
[2567913-75-9]
Formula:
C22H18N4OS
Target:
Microtubule Associated|||MicroRNA
T86892
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