NBI 35965 hydrochloride, CAS [[1782228-59-4]] Preis auf Anfrage

Product Overview

• Article Name: NBI 35965 hydrochloride, CAS [[1782228-59-4]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T86978
• Supplier Catalog Number: T86978
• Alternative Catalog Number: TGM-T86978-10MG,TGM-T86978-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

NBI 35965 hydrochloride is a selective CRF1 (corticotropin-releasing factor receptor 1) antagonist that is both orally active and capable of penetrating the brain. It possesses a K i value of 4 nM and a pK i of 8.5, and does not affect CRF2. This compound effectively diminishes CRF or stress-triggered ACTH (adrenocorticotropic hormone) production in vivo, demonstrating pIC 50 values of 7.1 and 6.9. Additionally, NBI 35965 hydrochloride exhibits anxiolytic properties [1] [2].

Product Properties

• Molecular Weight: 437.79
• CAS Number: [1782228-59-4]
• Formula: C21H23Cl3N4
• Target: CRFR

Images

T86978