NIC-12, a potent NLRP3 inhibitor, selectively reduces circulating IL-1ß levels in the LPS-endotoxemia mice model and inhibits NLRP3 inflammasome activation in mouse macrophages [1].
Molecular Weight:
462.01
CAS Number:
[2409826-23-7]
Formula:
C22H28ClN5O2S
Target:
NOD-like Receptor (NLR)
T87004
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