NP3-562 is a powerful, orally administered tricyclic NLRP3 inhibitor, demonstrating an IC50 of 214 nM. At a dosage of 30 mg/kg given orally (p.o.), NP3-562 effectively suppresses IL-1beta release in a mouse model of acute peritonitis [1].
Molecular Weight:
437.94
CAS Number:
[2409825-32-5]
Formula:
C19H24ClN5O3S
Target:
NOD-like Receptor (NLR)
T87031
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