NSC727447 is an inhibitor targeting ribonuclease H (Rnase H) in both HIV-1 and HIV-2. It exhibits minimal activity against E. coli RNase H, demonstrating significant selectivity for human Rnase H with IC50 values of 2.0 µM, 2.5 µM, 100 µM, and 10.6 µM, respectively [1].
Molecular Weight:
210.3
CAS Number:
[40106-12-5]
Formula:
C10H14N2OS
Target:
HIV Protease|||DNA/RNA Synthesis
T87039
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