OSM-S-106 is a pro-inhibitor that inhibits PfAsnRS through enzyme-mediated production of an Asn-OSM-S-106 adduct, inhibits protein translation, and activates the amino acid starvation response. OSM-S-106 exhibits selective activity against Plasmodium blood and liver stages and shows low intrinsic clearance by human microsomes [1].
Molecular Weight:
306.36
CAS Number:
[2650846-59-4]
Formula:
C12H10N4O2S2
Target:
Parasite
T87076
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