PDK4-IN-2 (compound 8), a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor, exhibits an inhibition concentration (IC 50) of 46 µM. By regulating bioenergetics and activating the tricarboxylic acid cycle [1], it enhances the ejection fraction in failing hearts.
Molecular Weight:
246.22
CAS Number:
[1616752-12-5]
Formula:
C13H10O5
Target:
Dehydrogenase
T87124
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