Compound B12 (PHGDH-IN-5) acts as a covalent inhibitor of PHGDH, demonstrating an IC50 value of 0.29 µM. It has been shown to inhibit the proliferation of cancer cell lines that overexpress PHGDH and reduce the production of glucose-derived serine in MDA-MB-468 cells [1].
Molecular Weight:
211.2
CAS Number:
[17402-86-7]
Formula:
C8H5NO4S
Target:
Dehydrogenase
T87143
* VAT and and shipping costs not included. Errors and price changes excepted
