PKM2-IN-6 (compound 7d) is an orally active PKM2 inhibitor (IC50=23 nM) capable of inducing apoptosis and G2 cell cycle arrest. It reduces PKM1 and PKM2 expression at the mRNA level, exhibits antitumour activity, and is suitable for investigating triple-negative breast cancer (TNBC).
Molecular Weight:
322.38
Purity:
99.83%
CAS Number:
[771467-00-6]
Formula:
C17H14N4OS
Target:
PKM|||Apoptosis
T87217
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