CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 µM). CTPI-2 inhibits glycolysis, PPARgamma, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet.
Molecular Weight:
356.74
Purity:
97.23%
CAS Number:
[68003-38-3]
Formula:
C13H9ClN2O6S
Target:
Mitochondrial Metabolism
T8732
* VAT and and shipping costs not included. Errors and price changes excepted