SB-1436 is a Cholinesterase (ChE) inhibitor that inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and recombinant human acetylcholinesterase (rHuAChE) with IC50 values of 0.176, 0.37, and 0.08 µM, respectively. It inhibits AChE and BChE in a non-competitive manner with Ki values of 0.046 and 0.115 µM, respectively. Additionally, SB-1436 significantly prevents the self-aggregation of Abeta and can be used for neurological disease research [1].
Molecular Weight:
405.89
CAS Number:
[2925298-08-2]
Formula:
C25H21ClFNO
Target:
Cholinesterase (ChE)
T87366
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