ARN25062 is an inhibitor of the protein-protein interaction between Cdc42 and p21-activated kinase (PAK). It inhibits the proliferation of SKM28, SK-MEL-3, WM3248, and A375 melanoma cells (IC50s = 6.1, 4.6, 9.3, and 5.1 µM, respectively) and SW480 colon cancer cells (IC50 = 5.9 µM).
Molecular Weight:
398.4
CAS Number:
[3036492-85-7]
Formula:
C22H21F3N4
Target:
Ras
T87956
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