DBPR728, an acyl prodrug of 6K465, possesses fewer hydrogen bond donors and functions as an Aurora kinase inhibitor that targets MYC family cancer proteins, showing antitumor potential. It can effectively inhibit cancers overexpressing C-MYC and N-MYC, offering a 10-fold improvement in oral bioavailability over 6K465.
Molecular Weight:
598.11
CAS Number:
[2702965-64-6]
Formula:
C29H37ClFN9O2
Target:
Aurora Kinase
T88056
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