PROTAC EGFR degrader 11, CAS [[3034244-71-5]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T88077
Supplier Catalog Number:
T88077
Alternative Catalog Number:
TGM-T88077-10MG,TGM-T88077-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader targeting the epidermal growth factor receptor (EGFR), with a DC50 of less than 100 nM. It binds to CRBN-DDB1 with a Ki of 36 nM. This compound effectively degrades EGFR, focal adhesion kinase (FAK), and RSK1, and inhibits the proliferation of BaF3 wild-type and EGFR mutant cells, exhibiting an IC50 of less than 100 nM.
Molecular Weight:
991.61
CAS Number:
[3034244-71-5]
Formula:
C49H64ClFN10O7S
Target:
EGFR|||FAK|||PROTACs
T88077
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