25-Hydroxytachysterol3 is a metabolite of Vitamin D3 that inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts while promoting the differentiation of keratinocytes and the expression of antioxidant-related genes. It activates receptors including the vitamin D receptor (VDR), aryl hydrocarbon receptor (AhR), liver X receptor alpha/beta (LXRalpha/beta), and peroxisome proliferator-activated receptor gamma (PPARgamma), and enhances the expression of CYP24A1.
Molecular Weight:
400.64
CAS Number:
[39932-44-0]
Formula:
C27H44O2
Target:
PPAR|||Vitamin|||Liver X Receptor|||Aryl Hydrocarbon Receptor
T88081
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