PT-88, a highly selective mTOR (Mammalian target of rapamycin) inhibitor (IC 50 =1.2 nM), effectively targets both mTORC1 and mTORC2 complexes. These complexes represent the active isoforms of mTOR protein kinases, integral to cell growth, proliferation, and survival. The utility of PT-88 extends to researching mTORs involvement in tumorigenesis and development, with significant applications in breast cancer treatments.
Molecular Weight:
569.61
CAS Number:
[2803307-04-0]
Formula:
C30H31N7O5
Target:
mTOR
T88090
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