SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pockets closed conformation.
Molecular Weight:
426.47
CAS Number:
[1255915-27-5]
Formula:
C22H26N4O5
Target:
CCR|||CXCR
T88146
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