Lurosetron (GR-87442) is the 6-fluoro analogue of Alosetron. It functions as a serotonin 5-HT3 receptor antagonist. Lurosetron inhibits recombinant (rbt) CYP1A2 with an IC50 of 0.1 µM and also inhibits other CYP subtypes, including rbtCYP2C9 and rbtCYP3A4, with IC50 values ranging from 3.5 µM to 16 µM.
Molecular Weight:
312.34
CAS Number:
[128486-54-4]
Formula:
C17H17FN4O
Target:
5-HT Receptor
T88171
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