Compound II15, known as XOR/URAT1-IN-1, serves as a dual inhibitor targeting xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1), exhibiting IC50 values of 6 nM and 12.9 µM, respectively. This compound effectively reduces uric acid levels in a mouse model of acute hyperuricemia induced by potassium oxonate and hypoxanthine.
Molecular Weight:
340.76
CAS Number:
[2810137-86-9]
Formula:
C18H13ClN2O3
Target:
OAT|||Xanthine Oxidase
T88230
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