B102 (PARP/HDAC-IN-1) is a dual inhibitor of PARP and HDAC, exhibiting IC50 values of 19.01 nM for PARP1, 2.13 nM for PARP2, 1.69 µM for HDAC1, and greater than 10 µM for HDAC6 in enzymatic assays. It possesses antiproliferative and antitumor properties and induces DNA damage and apoptosis in vitro.
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