AKR1C3-IN-14 (compound 4) is an inhibitor of AKR1C3 enzyme, exhibiting an IC50 value of 0.122 µM. It reduces excess androgen production by inhibiting the activity of the AKR1C3 enzyme, thereby regulating hormone-mediated signaling. Additionally, AKR1C3-IN-14 plays a role in the biosynthesis of prostaglandin PGF2alpha, influencing this pathway to regulate cell proliferation. This compound is utilized in the research of prostate cancer.
Molecular Weight:
445.31
CAS Number:
[1057882-82-2]
Formula:
C21H21BrN2O4
Target:
Reductase
T88498
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