MYX1715 is an inhibitor of N-myristoyltransferase (NMT), exhibiting a KD of 0.09 nM. It inhibits the proliferation of LU0884 and LU2511, with IC50 values of 44 nM and 9 nM, respectively. In mouse models, MYX1715 demonstrates antitumor activity against neuroblastoma and gastric cancer. Additionally, MYX1715 can be utilized as a toxin in ADCs.
Molecular Weight:
480.99
CAS Number:
[2445448-66-6]
Formula:
C25H29ClN6O2
Target:
ADC Cytotoxin
T88528
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