CCR1 antagonist12 (Compound 12) is an antagonist of CCR1, exhibiting an IC50 of 3 nM against human CCR1. It inhibits the chemotaxis through pores induced by CCL3, with an IC50 of 0.009 µM. Additionally, CCR1 antagonist12 demonstrates favorable pharmacokinetic properties in a rat model.
Molecular Weight:
487.95
CAS Number:
[921208-19-7]
Formula:
C25H27ClFN3O4
Target:
CCR
T88578
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