Antibiofilm agent-9 (Compound 4), a derivative of pyrrolnitrin, exhibits antimicrobial activity. It inhibits Bacillus anthracis with a Minimum Inhibitory Concentration (MIC) of 0.031 µg/mL. The compound demonstrates significant antibiofilm activity, achieving an inhibition rate of 84% after 24 hours at a concentration of 8.0 µg/mL. Additionally, Antibiofilm agent-9 shows favorable pharmacokinetic properties in mouse models.
Molecular Weight:
352.97
CAS Number:
[2001602-07-7]
Formula:
C11H5BrCl2FNO2
Target:
Antibacterial
T88641
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