BSJ-5-63 is an effective degrader of CDK12, CDK7, and CDK9. It reduces the protein expression of CDK12, CDK7, CDK9, RNAPII, and Cyclin K, and also decreases the mRNA expression of BRCA1 and BRCA2. BSJ-5-63 exhibits anticancer activity and holds potential for prostate cancer research.
Molecular Weight:
1020.78
CAS Number:
[2519823-37-9]
Formula:
C52H74ClN9O6S2
Target:
PROTACs|||CDK
T88693
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