Angelylalkannin, a naphthoquinone compound isolated from the roots of Alkanna tinctoria, exhibits significant antiproliferative effects on human colon cancer cells HCT-116 and SW-480. The median inhibitory concentration (IC50) of Angelylalkannin is 4.76 mM for HCT-116 cells and 7.03 mM for SW-480 cells. Similar to alkannin, Angelylalkannin induces cell cycle arrest in the G1 phase and cell apoptosis at concentrations ranging from 1-10 mM.
Molecular Weight:
370.4
CAS Number:
[69175-72-0]
Formula:
C21H22O6
T88955
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